Study # 2250 – Group 3

Population:

Healthy, Recreational OPIOID users; Males and non-pregnant Females, 18-55 years of age; free of daily medications.

Study Details:

3 visits (Screening/ Qualification/ Treatment/ Follow-up).  Compensation is up to $7000 for completing the entire study.

Study Date

Visit 2:  20-days (19-nights) continuous in-clinic stay

 VISIT 1 – SCREENING VISIT
 VISIT 2 – QUALIFICATION PHASE
Clinic Admission/ Naloxone Challenge Wednesday Aug 08, 2018  @ 8 am
Qualification Dose 1 Thursday Aug 09, 2018
Qualification Dose 2 Friday Aug 10, 2018
Exit – Qualification Failures OR

In-clinic (non-dose) – Qualification Passes

Saturday Aug 11, 2018 @ 12 noon
 VISIT 2 – TREATMENT PHASE (continued)
In-clinic (non-dose) Sunday Aug 12, 2018
Treatment Dose 1 Monday Aug 13, 2018
In-clinic (non-dose) Tuesday Aug 14, 2018
In-clinic (non-dose) Wednesday  Aug 15, 2018
Treatment Dose 2 Thursday  Aug 16, 2018
In-clinic (non-dose) Friday  Aug 17, 2018
In-clinic (non-dose) Saturday Aug 18, 2018
Treatment Dose 3 Sunday Aug 19, 2018
In-clinic (non-dose) Monday Aug 20, 2018
In-clinic (non-dose) Tuesday Aug 21, 2018
Treatment Dose 4 Wednesday Aug 22, 2018
In-clinic (non-dose) Thursday Aug 23, 2018
In-clinic (non-dose) Friday Aug 24, 2018
Treatment Dose 5 Saturday Aug 25, 2018
In-clinic (non-dose) Sunday Aug 26, 2018
Exit – Treatment Monday Aug 27, 2018 @ 12 noon
 VISIT 3 – FOLLOW-UP
 Post Study Follow-up Thursday, August 30, 2018

Post Study Visit:

N/A

Additional Info:

Morning drug administration on an empty stomach

Contact:

Toll Free 1-833-879-2774 or (416) 747-5246